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Expediente Edição 10

Colaboradores desta edição

Veja também as referências bibliográficas clicando aqui

  • Gerente de Pesquisa e Desenvolvimento – Huntington Medicina Reprodutiva – Eugin Group, São Paulo, SP, Brasil.
  • Pós-Doutoranda do Departamento de Biologia Celular e do Desenvolvimento, Instituto de Ciências Biomédicas, Universidade de São Paulo, São Paulo, SP, Brasil. Período Sanduíche no Instituto de Fisiologia, Desenvolvimento e Neurociências da Universidade de Cambridge, Cambridge, Reino Unido.
  • Doutoranda do Departamento de Biologia Celular e do Desenvolvimento, Instituto de Ciências Biomédicas, Universidade de São Paulo, São Paulo, SP, Brasil. Período Sanduíche no Departamento de Ginecologia, Obstetrícia e Ciências da Reprodução da Faculdade de Medicina da Universidade da Califórnia San Francisco (UCSF), San Francisco, CA, Estados Unidos.
  • Treinamento em Embriologia – Huntington Medicina Reprodutiva. São Paulo, SP, Brasil.
  • Iniciação Científica em Implantação Embrioná Departamento de Biologia Celular e do Desenvolvimento, Instituto de Ciências Biomédicas, Universidade de São Paulo, São Paulo, SP, Brasil.
  • Graduação em Ciências Biológicas. Universidade de São Paulo, São Paulo, SP, Brasil.
  • Graduação em Medicina pela Faculdade de Medicina de Ribeirão Preto – USP
  • Residência Médica em Ginecologia e Obstetrícia no HC FMRP – USP
  • Especialização em Reprodução Humana pelo HC FMRP – USP
    Mestrado em Reprodução Humana pela FMRP – USP
  • Doutorado em andamento pela FMRP – USP
  • Título de Especialista em Ginecologia e Obstetrícia – FEBRASGO e AMB
  • Título de Especialista – Área de Atuação em Ultrassonografia em Ginecologia e Obstetrícia – AMB, CBR e FEBRASGO
  • Título de Especialista – Área de Atuação em Reprodução Humana – FEBRASGO e AMB.
  • Médica ginecologista e obstetra em consultório particular e integrante do corpo clínicio da Unimed Ribeirão Preto.
  • Médica Ginecologista e Obstetra
  • Doutorado e Mestrado em Tocoginecologia pela UNICAMP
  • Especialista em Reprodução Humana ( Título pela FEBRASGO)
  • Graduada em Ciências Biológicas, na modalidade Bacharelado, na Universidade Federal de Pernambuco (UFPE).
  • Mestranda do Laboratório de Estudos da Interação Materno-Fetal e Placenta , do programa de Biologia de Sistemas (ICB-USP).
  • Possui experiência em bioquímica e embriologia.
  • Bacharel em Ciências Biológicas modalidade Médica pela Faculdade de Ciências Médicas e Biológicas de Botucatu – Universidade Estadual Paulista “Júlio Mesquita Filho” (UNESP).
  • Doutora em Biologia Celular e Tecidual por estudos de implantação embrionária em modelos murinos, pela Universidade de São Paulo (USP).
  • Pós-Doutora pela University of California San Francisco, UCSF (EUA).
  • Professora-Titular do Instituto de Ciências Biomédicas da Universidade de São Paulo (ICB-USP).
  • Coordenadora do Laboratório de Estudos da Biologia do Trofoblasto no Departamento de Biologia Celular e do Desenvolvimento do ICB-USP.
  • Fundadora da Sociedade Latino-Americana de Interação Materno-Fetal & Placenta (SLIMP) e membro da Placenta Associations of the Americas.
  • Principal área de atividade científica é o estudo das interações trofoblasto-endométrio, com foco nos mecanismos de regulação durante a implantação e formação da placenta humana e de camundongos.
  • Fellowship em Fertilidade Masculina e Microcirurgia pela Weill Cornell Medicine, New York-NY
  • Pós Graduado em Reprodução Assistida pela Santa Casa de São Paulo
  • Mestre em Cirurgia pela Universidade Federal de Pernambuco (UFPE)
  • Diretor clínico – Clínica Andros Recife – Recife-PE
  • Graduada em Biomedicina pela Universidade Paulista (UNIP).
  • Habilitada em biologia molecular e pós-graduada em Análises Clínicas.
  • Mestranda do Laboratório de Estudos da Interação Materno-Fetal e Placenta, do programa de Biologia de Sistemas (ICB-USP), desenvolvendo pesquisa com células placentárias humanas.
  • Departamento de Obstetrícia e Ginecologia, Universidade Federal da Bahia (UFBA), Salvador, BA
  • Programa de Pós-Graduação em Ciências Médicas, Universidade de Fortaleza (UNIFOR, Fortaleza, CE)
  • CONCEPTUS – Medicina Reprodutiva, Fortaleza, CE
  • Professora Associada do Departamento de Ginecologia e Obstetrícia da Faculdade de Medicina de Ribeirão Preto – USP, Setor de Reprodução Humana.
  • Diretora do Laboratório de Reprodução Assistida do Hospital das Clínicas de Ribeirão Preto-USP (HCRP-USP).
  • Coordenadora dos Ambulatórios de Fertilidade (AFERT) e Infertilidade (AEST) do HCRP-USP.
  • Diretora de Comunicações da Sociedade Brasileira de Reprodução Humana (SBRH)
  • Membro da Comissão Nacional Especializada de Reprodução Assistida da FEBRASGO
  • Departamento de Obstetrícia e Ginecologia, Universidade Estadual de Campinas (UNICAMP), Campinas, SP
  • Bacharel Ciências Biológicas com Ênfase em Biotecnologia pela universidade do Vale do Itajaí, trabalhando como bolsista do Laboratório de Biotecnologia da Reprodução (LBR).
  • Especialista em Embriologia Humana e Fertilização In vitro (FIV) pelo Instituto Sapientiae (São Paulo).
  • Doutor em Ciências pelo departamento Biologia Celular e Tecidual, Instituto de Ciências Biomédicas da Universidade de São Paulo (USP), estudando o processo de implantação de embrionária em Camundongos.
  • Coordenador do Transgenic Mice, ICSI and IVF Core (Institute for Biogenesis Research – John A. Burns School of Medicine – University of Hawaii at Manoa), responsável pelo desenvolvimento de animais geneticamente modificados, treinamento e desenvolvimentos de novas tecnologias em reprodução assistida humana e animal.
  • Colaborador em projetos de pesquisa focados no estudo da biologia das células do trofoblasto do blastocisto à placenta, assim como a comunicação celular local e sistêmica mediada por pequenas vesículas extracelulares.
  • Tocoginecologista atuante nas áreas de Ginecologia, Obstetrícia, Reprodução Assistida e Cirurgia Endoscópica.
  • Médico Ginecologista e Obstetra do Instituto Paulista de Ginecologia, Obstetrícia e Medicina Reprodutiva (IPGO – São Paulo – SP)
  • Médico Assistente na área de Ginecologia do Centro de Atenção Integral à Saúde da Mulher (CAISM/ UNICAMP).
  • Responsável Técnico pelo Laboratório de Reprodução Humana do Centro de Atenção Integral à Saúde da Mulher (CAISM/ UNICAMP).
  • Mestre pela Departamento de Tocoginecologia da Universidade Estadual de Campinas (UNICAMP).
  • Título de Especialista pela Federação Brasileira de Ginecologia e Obstetrícia (FEBRASGO) (TEGO 0732 / 2004) – RQE: 38912.
  • Certificado de Atuação em Reprodução Assistida pela FEBRASGO – Registro AMB: 182857 – RQE: 38912-1.
  • Bióloga, bacharel e    licenciada,   pela    Universidade   Estadual   de    Campinas (UNICAMP).
  • Especialista em Reprodução    Humana    Assistida    pela    Associação    Instituto Sapientiae.
  • Mestranda em Biologia de Sistemas, em estudo sobre Biologia do Trofoblasto, pela Universidade de São Paulo (ICB-USP).
  • Assessora de mídias na Liga Acadêmica de Embriologia e Reprodução da USP.
  • Possui experiência em reprodução animal e humana.

Referências bibliográficas

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  2. E Giacomini, E Alleva, G Fornelli, A Quartucci, L Privitera, V S Vanni, P Viganò, Embryonic extracellular vesicles as informers to the immune cells at the maternal–fetal interface, Clinical and Experimental Immunology, Volume 198, Issue 1, October 2019, Pages 15–23
  3. Nan-Xing, J. and Xue-Lian, L. The Complicated Effects of Extracellular Vesicles and Their Cargos on Embryo Implantation. Frontiers in Endocrinology v.12, p. 659, 2021.
  4. Kurian, N.K., Modi, D. Extracellular vesicle mediated embryo-endometrial cross talk during implantation and in pregnancy. J Assist Reprod Genet36, 189–198 (2019)

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(1) Verma S, King A, Loke YW. Expression of killer cell inhibitory receptors on human uterine natural killer cells. Eur J Immunol. 1997 Apr;27(4):979-83. (2) Feyaerts D, Kuret T, van Cranenbroek B, van der Zeeuw-Hingrez S, van der Heijden OWH, van der Meer A, Joosten I, van der Molen RG. Endometrial natural killer (NK) cells reveal a tissue-specific receptor repertoire. Hum Reprod. 2018 Mar 1;33(3):441-451. (3) Moffett A, Chazara O, Colucci F, Johnson MH. Variation of maternal KIR and fetal HLA-C genes in reproductive failure: too early for clinical intervention. Reprod Biomed Online. 2016 Dec;33(6):763-769. (4) Hiby SE, Walker JJ, O’shaughnessy KM, Redman CW, Carrington M, Trowsdale J, Moffett A. Combinations of maternal KIR and fetal HLA-C genes influence the risk of preeclampsia and reproductive success. J Exp Med. 2004 Oct 18;200(8):957-65. (5) Hiby SE, Regan L, Lo W, Farrell L, Carrington M, Moffett A. Association of maternal killer-cell immunoglobulin-like receptors and parental HLA-C genotypes with recurrent miscarriage. Hum Reprod. 2008 Apr;23(4):972-6. (6) Hiby SE, Apps R, Sharkey AM, Farrell LE, Gardner L, Mulder A, Claas FH, Walker JJ, Redman CW, Morgan L, Tower C, Regan L, Moore GE, Carrington M, Moffett A. Maternal activating KIRs protect against human reproductive failure mediated by fetal HLA-C2. J Clin Invest. 2010 Nov;120(11):4102-10. (7) Hiby SE, Apps R, Chazara O, Farrell LE, Magnus P, Trogstad L, Gjessing HK, Carrington M, Moffett A. Maternal KIR in combination with paternal HLA-C2 regulate human birth weight. J Immunol. 2014 Jun 1;192(11):5069-73. (8) Xiong S, Sharkey AM, Kennedy PR, Gardner L, Farrell LE, Chazara O, Bauer J, Hiby SE, Colucci F, Moffett A. Maternal uterine NK cell-activating receptor KIR2DS1 enhances placentation.J Clin Invest. 2013 Oct;123(10):4264-72. (9) Wang S, Li YP, Ding B, Zhao YR, Chen ZJ, Xu CY, Fu YB, Wang XT. Recurrent miscarriage is associated with a decline of decidual natural killer cells expressing killer cell immunoglobulin-like receptors specific for human leukocyte antigen C. J Obstet Gynaecol Res. 2014 May;40(5):1288-95. (10) Alecsandru D, Garrido N, Vicario JL, Barrio A, Aparicio P, Requena A, García-Velasco JA. Maternal KIR haplotype influences live birth rate after double embryo transfer in IVF cycles in patients with recurrent miscarriages and implantation failure. Hum Reprod. 2014 Dec;29(12):2637-43. (11) Alecsandru D, Barrio A, Garrido N, Aparicio P, Pellicer A, Moffett A, García-Velasco JA. Parental human leukocyte antigen-C allotypes are predictive of live birth rate and risk of poor placentation in assisted reproductive treatment. Fertil Steril. 2020 Oct;114(4):809-817. (12) Morin SJ, Treff NR, Tao X, Scott RT 3rd, Franasiak JM, Juneau CR, Maguire M, Scott RT. Combination of uterine natural killer cell immunoglobulin receptor haplotype and trophoblastic HLA-C ligand influences the risk of pregnancy loss: a retrospective cohort analysis of direct embryo genotyping data from euploid transfers. Fertil Steril. 2017 Mar;107(3):677-683.e2.
(1) Verma S, King A, Loke YW. Expression of killer cell inhibitory receptors on human uterine natural killer cells. Eur J Immunol. 1997 Apr;27(4):979-83. (2) Feyaerts D, Kuret T, van Cranenbroek B, van der Zeeuw-Hingrez S, van der Heijden OWH, van der Meer A, Joosten I, van der Molen RG. Endometrial natural killer (NK) cells reveal a tissue-specific receptor repertoire. Hum Reprod. 2018 Mar 1;33(3):441-451. (3) Moffett A, Chazara O, Colucci F, Johnson MH. Variation of maternal KIR and fetal HLA-C genes in reproductive failure: too early for clinical intervention. Reprod Biomed Online. 2016 Dec;33(6):763-769. (4) Hiby SE, Walker JJ, O’shaughnessy KM, Redman CW, Carrington M, Trowsdale J, Moffett A. Combinations of maternal KIR and fetal HLA-C genes influence the risk of preeclampsia and reproductive success. J Exp Med. 2004 Oct 18;200(8):957-65. (5) Hiby SE, Regan L, Lo W, Farrell L, Carrington M, Moffett A. Association of maternal killer-cell immunoglobulin-like receptors and parental HLA-C genotypes with recurrent miscarriage. Hum Reprod. 2008 Apr;23(4):972-6. (6) Hiby SE, Apps R, Sharkey AM, Farrell LE, Gardner L, Mulder A, Claas FH, Walker JJ, Redman CW, Morgan L, Tower C, Regan L, Moore GE, Carrington M, Moffett A. Maternal activating KIRs protect against human reproductive failure mediated by fetal HLA-C2. J Clin Invest. 2010 Nov;120(11):4102-10. (7) Hiby SE, Apps R, Chazara O, Farrell LE, Magnus P, Trogstad L, Gjessing HK, Carrington M, Moffett A. Maternal KIR in combination with paternal HLA-C2 regulate human birth weight. J Immunol. 2014 Jun 1;192(11):5069-73. (8) Xiong S, Sharkey AM, Kennedy PR, Gardner L, Farrell LE, Chazara O, Bauer J, Hiby SE, Colucci F, Moffett A. Maternal uterine NK cell-activating receptor KIR2DS1 enhances placentation.J Clin Invest. 2013 Oct;123(10):4264-72. (9) Wang S, Li YP, Ding B, Zhao YR, Chen ZJ, Xu CY, Fu YB, Wang XT. Recurrent miscarriage is associated with a decline of decidual natural killer cells expressing killer cell immunoglobulin-like receptors specific for human leukocyte antigen C. J Obstet Gynaecol Res. 2014 May;40(5):1288-95. (10) Alecsandru D, Garrido N, Vicario JL, Barrio A, Aparicio P, Requena A, García-Velasco JA. Maternal KIR haplotype influences live birth rate after double embryo transfer in IVF cycles in patients with recurrent miscarriages and implantation failure. Hum Reprod. 2014 Dec;29(12):2637-43. (11) Alecsandru D, Barrio A, Garrido N, Aparicio P, Pellicer A, Moffett A, García-Velasco JA. Parental human leukocyte antigen-C allotypes are predictive of live birth rate and risk of poor placentation in assisted reproductive treatment. Fertil Steril. 2020 Oct;114(4):809-817. (12) Morin SJ, Treff NR, Tao X, Scott RT 3rd, Franasiak JM, Juneau CR, Maguire M, Scott RT. Combination of uterine natural killer cell immunoglobulin receptor haplotype and trophoblastic HLA-C ligand influences the risk of pregnancy loss: a retrospective cohort analysis of direct embryo genotyping data from euploid transfers. Fertil Steril. 2017 Mar;107(3):677-683.e2.
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